18.03.18 18:12

Biology: Article in PNAS

Lessons from yeast may help tackle dementia

Schematic illustration of amyloid fibrils with parallel beta sheet structures, such as also occur in the prion in question. (Illustration: HHU / Henrike Heise)

Together with Japanese colleagues, biophysicists at Heinrich Heine University Düsseldorf (HHU) and Jülich Research Centre have examined the folding of specific proteins in yeast fungi. They discovered similar mechanisms to those found in prions, i.e. proteins that are misfolded and can trigger neurodegenerative diseases. From the prions in yeast, the researchers were able to acquire new insights into the misfolding of these harmful proteins. Their results have been published in the scientific journal Proceedings of the National Academy of Sciences (PNAS).

Responsible for the content: E-MailStabsstelle Presse und Kommunikation