Pietruszka Group

Group leader

Title	Name	First Name	Position
Prof. Dr.	Pietruszka	Jörg	Head of Institute

 For more information on the principal investigator click here...

BioStruct Fellow

Title	Name	First Name	Position
Msc.	Classen	Thomas	PhD student

 For more information on the biostruct fellow click here...

Further Team Members

Technicians:	6
Master/Diploma students:	6
PHD/MD students:	16

Contact

Jörg Pietruszka
Institute of Bioorganic Chemistry
Forschungszentrum Jülich
Stetternicher Forst, Geb. 15.8
52426 Jülich

 +49(0)2461-614158
 +49(0)2461-616196


website:
http://www.iboc.uni-duesseldorf.de/

Special Methodical Expertise

• Applied Biocatalysis
• Assay Development

 click here for further information

Main areas of research interest

• Natural Product Synthesis
• Organoboron Chemistry
• Biocatalysis
• Assay Development
• Enantioselectivity Screening

Facilities

The laboratories cover the following gene technology security levels:

S1

Laboratory Equipment

General equipment available in the laboratories:

• Biotechnology
• Org. Chemistry

Special equipment, which is not generally available in most laboratories:

• HTS-NMR
• HTS-HPLC/CD

Non-standard methods, which are established in the laboratory:

• Chemoenzymatic total synthesis of natural products
• Utilizing stable boronic esters

Important References

• Luithle, J. E. A., Pietruszka, J. (1999). Synthesis of Enantiomerically Pure Cyclopropanes from Cyclopropylboronic Acids. J. Org. Chem. 64, 8287-8297.
• Pietruszka, J. (2003). Synthesis and Properties of Oligocyclopropyl-Containing Natural Products and Model Compounds. Chem. Rev. 103, 1051-1070.
• Pietruszka, J., Schöne, N. (2003). [3,3]-Sigmatrope Umlagerungen von Bor-haltigen Allylalkoholen: Synthese von Allyladditionsreagentien. Angew. Chem. 115, 5796-5799.
• Pietruszka, J., Rieche, A. C. M. (2008). Total Synthesis of Marine Oxylipins Solandelactones A-H. Adv. Syn. Catal. 350, 1407-1412.
• Pietruszka, J., Schöne, N., Frey, W., Grundl, L. (2008). Diastereo- and Enantiomerically Pure Allylboronates: Their Synthesis and Scope. Chem. Eur. J. 14, 5178-5197.