Oesterhelt Group

Group leader

Title	Name	First Name	Position
Akad. Rat Dr.	Oesterhelt	Filipp	Group leader

 For more information on the principal investigator click here...

Researchers

Title	Name	First Name	Position
Dr.	N.N.		Postdoc
Dr.	N.N.		Postdoc
	N.N.		Doctoral Researcher

BioStruct Fellow

Title	Name	First Name	Position
	N.N.		Doctoral Researcher
MSc	Roychoudhury	Arpita	Doctoral Researcher

 For more information on the biostruct fellow click here...

Further Team Members

Technicians:	1
Master/Diploma students:	1
PHD/MD students:	3

Contact

AG Nanoanalytik
Institut für Physikalische Biologie
Heinrich Heine Universität Düsseldorf
Universitätsstr. 1
40225 Düsseldorf

+49(0)211-81-13805


website:
http://www.mpc.uni-duesseldorf.de/nanoanalytik/index.htm

Expertise in Structural Biology

• Atomic Force Microscopy
• Force Spectroscopy
• Single Molecule Fluorescence Spectroscopy

 click here for further information

Main areas of research interest

• Membrane protein structure and stability
• Forces of ABC transporters
• Protein - RNA interactions
• nanopatterning of surfaces via nano-manipulation

Laboratory Equipment

General equipment available in the laboratories:

• Biophysics
• Imaging

Special equipment, which is not generally available in most laboratories:

• Time resolved multi colour fluorescence detection setup
• CCD Camera for fluorescence detection with single molecule sensitive
• Atomic Force Microscope with simultaneous fluorescence detection (CCD camera)

Important References

• A. Woźniak, G. Schröder, H. Grubmüller, C. Seidel, F. Oesterhelt, " Single molecule FRET measures bends and kinks in DNA" PNAS, in press
• D.Cisneros, L. Oberbarnscheidt, A. Pannier, J. Klare, J. Helenius, M. Engelhard, F. Oesterhelt, D. J. Müller "Transducer binding establishes localized interactions that tune sensory rhodopsin II" Structure, Structure (2008) 16, 1206-13
• V. Kudryavtsev, S. Felekyan, A. Woźniak, M. König, C. Sandhagen, R. Kühnemuth, C. Seidel, F. Oesterhelt, "Multiparameter Fluorescence Imaging to Monitor Dynamic Systems". Anal Bioanal Chem (2007) 387, 71-82.
• A. Wozniak, S. Nottrott, E. Kühn-Hölsken, G. Schröder, H. Grubmüller, R. Lührmann, C. Seidel, F. Oesterhelt, "Detecting protein-induced folding of the U4 snRNA kink-turn by single-molecule multiparameter FRET measurements" RNA (2005) 11, 1545-1554.
• F. Oesterhelt, D. Oesterhelt, M. Pfeiffer, A. Engel, H. E. Gaub, D. J. Müller, "Unfolding pathways of individual Bacteriorhodopsins" Science (2000) 288, 143-146

Cooperators

• Müller, Daniel, Prof. Dr., University of Dresden, Germany
• Engelhard, Martin, Prof. Dr., Max Planck Institute for molecular physiology, Dortmund, Germany
• Rodnina, Marina, Prof. Dr., Max Planck Institute for biophysical Chemistry, Göttingen, Germany
• Wintermeier, Wolfgang, Prof. Dr., University Witten Herdecke, Germany
• Piehler, Jacob, Prof. Dr., University Osnabrück