Dr. Volker R. Stoldt

Volker R. Stoldt Dept. Hemostasis and Transfusion Medicine Heinrich Heine University Medical Center Moorenstrasse 5 40225 Düsseldorf Germany +49(0)211 8116916 +49(0)211 8119230 website:  www.uniklinik-duesseldorf.de/transfusionsmedizin

Publications

Special Methodical Expertise

• Flow simulation by in vitro flow models and rheometer
• Multiparametric confocal laser scanning microscopy and 3D-imaging
• Multiparametric flow cytometrie and fluorescence imaging

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Main areas of research interest

• Structure and function of integrins
• Mechanotransduction and biomechanic stress
• Protein interactions and cytoskeletal functions/reinforcement

Research Group and Equipment

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BioStruct Research Project

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Important references

• Stoldt VR, Peveling J, Loncar R, Beck A, Aurich V, Scharf RE. (2005) Evaluation of platelet thrombus formation under flow. Blood, 106: 70-71.
• Loncar R, Stoldt V, Hellmig S, Zotz RB, Mihalj M, Scharf RE. (2007) HPA-1 polymorphism of alphaIIbbeta3 modulates platelet adhesion onto immobilized fibrinogen in an in-vitro flow system. Thromb J., 5:2.
• Loncar R, Kalina U, Stoldt V, Thomas V, Scharf RE, Vodovnik A. (2006) Antithrombin significantly influences platelet adhesion onto immobilized fibrinogen in an in-vitro system simulating low flow. Thromb J., 4:19.
• Stoldt VR, Schnorr O, Schulze-Osthoff K, Scharf RE. (2006) Transforming growth factor-beta1 enhances the antifibrinolytic and prothrombotic state of growing endothelial cells in a cell cycle-specific manner. FASEB J., 20:965-6.
• Stoldt VR, Sonneborn A, Leuker CE, Ernst JF. (1997) Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi. EMBO J., 16:1982-91.