Prof. Dr. Dieter Häussinger

Clinic for Gastroenterology, Hepatology and Infectiology University Hospital Düsseldorf Heinrich Heine University Düsseldorf Moorenstr. 5 40225 Düsseldorf  +49(0)211-81-17569  +49(0)211-81-18838 website:  www.uniklinik-duesseldorf.de

Curriculum Vitae & Publications

 List of Publications

Special Methodical Expertise

• FRET and TIRF microscopy
• Live cell imaging/cell observer
• Liver perfusion, liver cell isolation and primary liver cell culture
• Stem cell biology
• Astrocyte biology and hepatic encephalopathy

Main areas of research interest

• Clinical and Experimental Hepatology
• Cell hydration and cell function
• Apoptosis and liver regeneration

Research Group and Equipment

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BioStruct Research Project

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Important references

• Häberle, J., Görg, B., Rutsch, F., Schmidt, E., Toutain, A., Benoist, J.F., Gelot, A., Suc, A.L., Höhne, W., Schliess, F., Häussinger, D. & Koch, H.G. (2005) Congenital systemic glutamine deficiency with glutamine synthetase mutations. New Engl. J. Med. 353, 38-45
• Warskulat, U., Borsch, E., Reinehr, R., Hell-Stilb, B., Mönnighoff, I., Buchzyk, D., Donner, M., Flögel, U., Kappert, G., Soboll, S., Beer, S., Pfeffer, K., Marschall, U., Gabrielsen, M., Amiry-Moghaddam, M., Dienes, H.P. & Häussinger, D. (2006) Chronic liver disease is triggered by taurine transporter knockout in the mouse. FASEB J. 20, 574-576
• Lang, P.A., Schenck, M., Nicolay, J.P., Becker, J., Kempe, D.S., Lupescu, A., Eisele, K., Klarl, B.A., Rübben, H., Schmidt, K.W., Mann, K., Hildenbrand, S., Huber, S.M., Wieder, T., Erhardt, A., Häussinger, D., Gulbins, S. E. & Lang, F. (2007) Liver cell death and anemia in Wilson´s disease involve acidic sphingomyelinase and ceramide. Nature Medicine, 13, 164-170
• Reinehr, R., Sommerfeld, A. & Häussinger, D. (2008) CD95 ligand is a proliferative and antiapoptotic signal in quiescent hepatic stellate cells. Gastroenterology 134, 1494-1506
• Görg, B., Qvartskhava, N., Keitel, V., Bidmon, H.J., Selbach, O., Schliess, F. & Häussinger, D. (2008) Ammonia induces RNA oxidation in cultured astrocytes and brain in vivo. Hepatology, 48, 567-579