Dr. Eva Birkmann

Eva Birkmann ISB-3 / Structural Biochemistry Forschungszentrum Jülich Wilhelm-Johnen-Str. 52428 Jülich +49(0)211 8112342 +49(0)211 8115167

Publications

 List of Publications

Special Methodical Expertise

• Biophysical analysis of protein aggregation mechanisms
• Protein membrane interaction
• Purification and analysis of prion proteins from cell cultures and natural tissues

Main areas of research interest

• Neurodegenerative diseases
• Prions
• Membrane proteins
• Protein aggregation mechanism

Research Group and Equipment

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BioStruct Research Project

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Important references

• Birkmann E, Schäfer O, Weinmann N, Dumpitak C, Beekes M, Jackman R, Thorne L, Riesner D. (2006) Detection of prion particles in samples of BSE and scrapie by fluorescence correlation spectroscopy without proteinase K digestion. Biol Chem. 387, 95-102
• Birkmann E., Henke F., Weinmann N., Dumpitak C., Funke SA., Willbold D., Riesner D. (2007) Counting of single prion particles bound to a capture-antibody surface (surface-FIDA) Vet. Microbiol. 123, 294-304
• Stöhr J., Weinmann N., Wille H., Kaimann K, Nagel-Steger L., Birkmann, E., Panza G., Prusiner SB., Eigen M. & Riesner D. (2008) Mechanisms of prion protein assembly into amyloid, Proc Natl Acad Sci U S A., 105(7): 2409-2414
• Birkmann E. & Riesner D., (2008) Prion infection – seeded fibrillization or more?, Prion, 2 (2), 67-72
• Panza G, Stöhr J, Dumpitak C, Papathanassiou D, Weiss J, Riesner D, Willbold D, Birkmann E. (2008), Spontaneous and BSE-prion-seeded amyloid formation of full length recombinant bovine prion protein, Biochem Biophys Res Commun. ;373(4):493-7.