Ms. Claudia Börger

Willbold Group Institute of Molecular Biophysics II Research Center Jülich GmbH Leo Brandt Straße, Geb. 05.2, Raum 2009 52425 Jülich, Germany  +49(0)2461-61-6517  +49(0)2461-61-2023

Mini Academic CV

University degrees:

First degree or intermediate examination:

• Bachelor of Science (Molecular Biotechnology), Technical University of Munich, Freising, Germany

Second degree and/or intermediate examination:

• Master of Science (Molecular Biotechnology), Technical University of Munich, Freising, Germany

Publications:

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Attended conferences:

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Prices/Scholarships:

• "Mayor of Freising award" for best master thesis in biological sciences
• Travel grant of the DAAD (German Academic Exchange Service)
• Award of the "Deutsche Physikalische Gesellschaft" for excellent results in physics
• From 01/2011 to 12/2013: Full scholarship of the NRW-Research School BioStruct, Heinrich Heine University, Düsseldorf, Germany

BioStruct PhD project

Protein Structure Determination using NMR Spectroscopy
Sperm can respond to a single molecule of chemoattractant released by an egg. The mechanism underlying this extreme sensitivity is unknown. Crucial signaling events in the response of sperm to chemoattractant include the rapid synthesis of the intracellular messenger guanosine 3',5'-monophosphate (cGMP) and the ensuing membrane hyperpolarization that results from the opening of potassium-selective cyclic nucleotide-gated (CNGK) channels. In this project using liquid NMR spectroscopy the 3D structures of newly characterised cyclic nucleotide-binding domains of sperm cells in apo and holo states shall be solved.


Topic Supervisor: Prof. Dr. Dieter Willbold, Institute for Physical Biology, Willbold Group

Complementary Supervisor:   Institute for  

BioStruct Fellow: Ms. Claudia Börger

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