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Stoldt, V.R., Sonneborn, A., Leuker, C. and Ernst, J.F. (1997) Efg1, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi. EMBO J. 16,1982-1991. Leuker, C.E., Sonneborn, A., Delbrück, S. and Ernst, J.F. (1997) Sequence and regulation of the PCK1 gene encoding phosphoenolpyruvate carboxykinase of the fungal pathogen Candida albicans. Gene 192,235-240. Delbrück, S., Sonneborn, A., Gerads, M., Grablowitz, A. and Ernst, J.F. (1997) Characterization and coordinate regulation of genes encoding ribosomal protein genes L39, S7 and L29 of the human pathogen Candida albicans. Yeast 13,1199-1210. Wickert, S., Finck, M., Herz, B. and Ernst, J. F. (1998) A small protein (Ags1p) and the Pho80p-Pho85p kinase complex contribute to aminoglycoside antibiotic resistance of the yeast Saccharomyces cerevisiae. J. Bacteriol. 180,1887-1894. Timpel, C., Strahl-Bolsinger, S., Ziegelbauer, K. and Ernst, J.F. (1998) Protein O-mannosylation by Pmt1p determines morphogenesis, adherence, susceptibility to antifungals and virulence of the fungal pathogen Candida albicans. J. Biol. Chem. 273,20837-20846. Rademacher, F., Kehren, Stoldt, V.R. and Ernst, J.F. (1998) Chaperonins as specific dominant-negative suppressors of fungal morphogenesis and RAS signal transduction pathways. Microbiology 114,2951-2960. Gerads, M. and Ernst, J.F. (1998) Overlapping coding regions of two essential chromosomal genes (CCT8, TRP1) in the fungal pathogen Candida albicans. Nucl. Ac. Res. 26,5061-5066. Lorberg, A., Kirchrath, L., Ernst, J.F. and Heinisch, J.J. (1999) Genetic and biochemical characterization of phosphofructokinase from the opportunistic pathogenic yeast Candida albicans. Eur. J. Biochem. 259,1-11. Sonneborn, A., Tebarth, B. and Ernst, J.F. (1999) Control of white-opaque phenotypic switching in Candida albicans by the Efg1p morphogenetic regulator. Infect. Immun. 67,4655-4660. Sonneborn, A., Bockmühl, D.P. and Ernst, J.F. (1999) Chlamydospore formation in Candida albicans requires the Efg1p morphogenetic regulator. Infect. Immun. 67,5514-5517. Heymann, P., Ernst, J.F. and Winkelmann, G. (1999) Identification of a fungal triacetylfusarinine C siderophore transport gene (TAF1) in Saccharomyces cerevisiae as a member of the major facilitator superfamily. Biometals 12,301-306. Weide, M., Tebarth, B. and Ernst, J.F. (1999) Caco-2 monolayer as a model for transepithelial migration of the fungal pathogen Candida albicans. Mycoses 42, (Suppl. 2), 61-67. Sonneborn, A., Bockmühl, D. P., Gerads; M., Kurpanek, K., Sanglard, D. and Ernst,J.F. (2000) Protein kinase A encoded by TPK2 regulates dimorphism of the human pathogen Candida albicans. Mol. Microbiol. 35,386-396. Ernst, J.F. (2000) Regulation of dimorphism in Candida albicans. In: Dimorphism in human pathogenic and apathogenic yeasts (edts. J.F. Ernst and A. Schmidt), Contributions to Microbiology 5, 98-111. Timpel, C., Zink, S., Strahl-Bolsinger, S., Schröppel, K. and Ernst, J. (2000) Morphogenesis, adhesive properties and antifungal resistance depend on the Pmt6 protein mannosyltransferase in the fungal pathogen Candida albicans. J. Bacteriol. 182, 3063-3071. Heymann, P., Ernst, J.F. and Winkelmann, G. (2000) Identification and substrate specificity of a ferrichrome-type siderophore transporter (Arn1p) in Saccharomyces cerevisiae. FEMS Microbiol. Lett. 186, 221-227. Heymann, P., Ernst, J.F. and Winkelmann, G. (2000) A gene of the major facilitator superfamily encodes a transporter for enterobactin (Enb1p) in Saccharomyces cerevisiae. Biometals 13, 65-72. Ernst, J.F. (2000) Transcription factors in Candida albicans: Environmental control of morphogenesis. Microbiology 146, 1829-1839. Weber, Y., Santore, U. J., Ernst, J. F. and Swoboda, R. K. (2001) Divergence of eukaryotic secretory components: the Candida albicans homolog to the Saccharomyces cerevisiae Sec20 protein is N-terminally truncated and its levels determine antifungal resistance and growth. J. Bacteriol. 183, 46-54. Bockmühl, D. P. and Ernst, J. F. (2001) A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albicans. Genetics 157, 1555-1567. Ernst, J. F. and Bockmühl, D. P. (2001) Gene expression and genetic techniques. In: Candida and Candidiasis, Editor R. Calderone, ASM Press Washington, 267-278. Ernst, J. F. and Prill, S. K.-H. (2001) O-glycosylation. Mol. Mycol. 39, Suppl. I, 67-74. Bockmühl, D. P., Krishnamurthy, S., Gerads, M., Sonneborn, A. and Ernst, J. F. (2001) Distinct and redundant roles of the two protein kinase A isoforms Tpk1p and Tpk2p in morphogenesis and growth of Candida albicans. Mol. Microbiol. 42, 1243-1257. Gruber, A., Lell, C. P., Speth, C., Stoiber, H., Lass-Florl, C., Sonneborn, A., Ernst, J. F., Dierich, M. P. and Würzner, R. (2001) Human immunodeficiency virus type 1 Tat binds to Candida albicans, inducing hyphae but augmenting phagocytosis in vitro. Immunology 104, 455-461. Heymann, P., Gerads, M., Schaller, M., Dromer, F., Winkelmann, G. and Ernst, J. F. (2002) The Sit1/Arn1 transporter of Candida albicans mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion. Infect. Immun. 70, 5246-5266. Weber, Y. and Ernst, J.F. (2002) Sec20p-interacting proteins (Tip20p, Ufe1p) in the retrograde secretory pathway of the fungal pathogen Candida albicans. Mol. Genet. Genom., 47, 89-102. Haas, H., Schoeser, M., Lesuisse, E., Ernst, J.F., Parson, W., Abt, B., Winkelmann, G. and Oberegger, H. (2003) Characterisation of the Aspergillus nidulans transporters for the siderophores enterobactin and triacetylfusarinine C. Biochem. J. 371, 505-513. Tebarth, B., Doedt, T., Krishnamurthy, S., Weide, M., Monterola, F., Dominguez, A. and Ernst, J.F. (2003) Adaptation of the Efg1p morphogenetic pathway in Candida albicans by negative autoregulation and PKA-dependent repression of the EFG1 gene. J. Mol. Biol. 329, 949 - 962. Krishnamurthy, S., Plaîne, A., Albert, J., Prasad, T., Prasad, R. and Ernst, J.F. (2004) Dosage-dependent functions of fatty acid desaturase Ole1p in growth and morphogenesis of Candida albicans. Microbiology 150, 1991-2003. Doedt, T., Krishnamurthy, S., Bockmühl, D. P., Tebarth, B., Stempel, C., Russell, C. L., Brown, A. J. P. and Ernst, J. F. (2004) APSES proteins regulate morphogenesis and metabolism in Candida albicans. Mol. Biol. Cell, 15, 3167-3180. Weber, Y., Prill, S. K.-H. and Ernst, J.F. (2004) Pmt-mediated O-glycosylation stabilizes an essential element of the secretory apparatus (Sec20p) in Candida albicans. Eukar. Cell 3, 1164-1168. Prill, S. K.-H., Klinkert, B., Timpel, C., Gale, C. A., Schröppel, K. and Ernst, J. F. (2005) PMT family of Candida albicans: five protein mannosyltransferase isoforms affect growth, morphogenesis and antifungal resistance. Mol. Microbiol., 55, 546-560. D'Enfert, C., Goyard, S., Rodriguez-Arnaveilhe, S., Frangeul, L., Jones, L., Tekaia, F., Bader, O., Albrecht, A., Castillo, L., Dominguez, A., Ernst, J. F., Fradin, C., Gaillardin, C., Garcia-Sanchez, S., de Groot, P., Hube, B., Klis, F. M., Krishnamurthy, S., Kunze, D., Lopez, M. C., Mavor, A., Martin, N., Moszer, I., Onesime, D., Perez-Martin, J., Sentandreu, R., Valentin, E., Brown, A. J. (2005) CandidaDB: a genomic database for Candida albicans pathogenomics. Nucl. Ac. Res. 33, D353-D357. Rouabhia, M., Schaller, M., Vecchiarelli, A., Prill, S. K.-H., Giasson, L. and Ernst, J. F. (2005) Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases (Pmt proteins). Infect. Immun. 73, 4571-4580. Pasrija, R., Krishnamurthy, S., Prasad, T., Ernst, J. F. and Prasad, R. (2005) Squalene epoxidase encoded by ERG1 affects morphogenesis and drug susceptibilities of Candida albicans. J. Antimicrob. Chemother. 55, 905-913. Setiadi, E. R., Doedt, T., Cottier, F., Noffz, C. and Ernst, J. F. (2006) Transcriptional response of Candida albicans to hypoxia: linkage of oxygen-sensing- and Efg1p-regulatory networks. J. Mol. Biol. 361, 399-411. (Selected article by "Faculty of 1000") Peltroche-Llacsahuanga, H., Goyard, S., D´Enfert, C., Prill, S. K.-H. and Ernst, J. F. (2006) Protein-O-mannosyltransferase-isoforms regulate biofilm formation of Candida albicans. Antimicrob. Agents Chemother. 50, 3488-3492. Cantero, P. D., Lengsfeld, C., Prill, S. K.-H., Subanović, M., Román, E., Pla, J. and Ernst, J. F. (2007) Transcriptional and physiological adaptation to defective protein-O-mannosylation in Candida albicans. Mol. Microbiol. 64, 1115-1128. Wittschier, N., Lengsfeld, C., Vorthems, S., Stratmann, U., Ernst, J. F., Verspohl, E. J., and Hensel, A. (2007) Large molecules as anti-adhesive compounds against pathogens. J. Pharm. Pharmacol. 50, 3488-3492. Corbucci, C., Cenci, E., Skrzypek, F., Gabrielli, E., Mosci, P., Ernst, J. F., Bistoni, F. and Vecchiarelli, A. (2007) Immune response to Candida albicans is preserved despite defect in O-glycosylation of secretory proteins. Med. Mycol. 45, 709 – 719. Lengeler, K., Tielker, D. and Ernst, J. F. (2008) Protein-O-mannosyltransferases in virulence and development. Cell. Mol. Life Sci. 65, 528-544. Noffz, C., Liedschulte, V. Lengeler, K., and Ernst, J. F. (2008) Functional mapping of the Candida albicans Efg1 regulator. Eukaryot. Cell, 7: 881-893. (Selected article by "Faculty of 1000") Fradin, C., Slomianny, M.C., Mille, C., Masset, A., Sundstrom, P., Ernst, J. F., Michalski, J.C., and Poulain, D. (2008) b-1,2 oligomannose adhesion epitopes are widely distributed over the four families of Candida albicans cell wall mannoproteins and associated through both N- and O-glycosylation processes. Infect. Immun. 76: 4509-4517. Ernst, J. F., and Tielker, D. (2009) Responses to hypoxia in fungal pathogens. Cell. Microbiol. 11: 183-190 Stichternoth, C., and Ernst, J. F. (2009) Hypoxic adaptation by Efg1 regulates biofilm formation of Candida albicans. Appl. Environ. Microbiol. 75: 3663-3672. Tielker, D., Eichhof, I., Jaeger, K.-E., and Ernst, J. F. (2009) FMN-based fluorescent protein as an oxygen-independent reporter in Candida albicans and Saccharomyces cerevisiae. Eukaryot. Cell 8: 913-915. Willger, S. D., Ernst, J. F., Alspaugh, J. A., and Lengeler, K. B. (2009) Characterization of the PMT gene family in Cryptococcus neoformans. PLoS ONE 4: e6321 Román, E., Cottier, F., Ernst, J. F. and Pla, J. (2009) The signaling mucin Msb2 controls the activation of the Cek1 MAP kinase in Candida albicans. Eukaryot. Cell 8: 1235-1249. Moreno, I., Martinez-Esparza, M., Laforet, L. C., Sentandreu, R., Ernst, J. F. and Valentin, E. (2009) Dosage-dependent roles of the Cwt1 transcription factor for cell wall architecture, morphogenesis, drug sensitivity and virulence in Candida albicans. Yeast 27: 77-87. Cantero, P. D. and Ernst, J. F. (2011) Damage to the glycoshield activates PMT-directed O-mannosylation via the Msb2-Cek1 pathway in Candida albicans. Mol. Microbiol. 80:715-725. Stichternoth, C., Fraund, A., Setiadi, S., Giasson, L., Vecchiarelli, A. and Ernst, J. F. (2011) Sch9 kinase integrates hypoxia and CO2 sensing to suppress hyphal morphogenesis in Candida albicans. Eukaryot. Cell 10:502-511. Ernst, J. F. and Pla, J. (2011) Signaling the glycoshield: maintenance of the Candida albicans cell wall. Int. J. Med. Microbiol.301:378-383. Buerth, C., Heilmann, C.J., Klis, F.M., de Koster, C.G., Ernst, J.F., and Tielker, D. (2011) Growth-dependent secretome of Candida utilis. Microbiology 157:2493-2503. Lassak, T., Schneider, E.,, Bussmann, M., Kurtz, D., Manak, J. R., Srikantha, T., Soll, D. R. and Ernst, J. F. (2011) Target specificity of the Candida albicans Efg1 regulator. Mol. Microbiol. 82: 602-618. (Selected article by "Faculty of 1000" Szafranski-Schneider, E., Swidergall, M., Cottier, F., Tielker, D., Román, E., Pla, J., and Ernst, J. F. (2011) Msb2 shedding protects Candida albicans against antimicrobial peptides. PLoS Pathogens, in press.
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