Publications

  1. Müschen M, Sies H and Schulz WA. Induction of mouse embryonal carcinoma cell differentiation and activation of the retinoic acid receptor b2 promotor by 1,25 dihydroxyvitamin D3. Biol Chem 1996; 377: 703-71
  2. Müschen M, Warskulat U, Douillard P, Gilbert E and Häussinger D. Regulation of CD95 (Apo-1/ Fas) receptor and ligand expression by Lipopolysaccharide and Dexamethasone in parenchymal and non-parenchymal rat liver cells. Hepatology 1998; 27: 200-208 (Full Article; pdf file)
  3. Müschen M, Warskulat U, Häussinger D, Moers C, Simon D and Even J. Deranged CD95 system in a case of Churg-Strauss vasculitis. Gastroenterology 1998; 114: 1351-1352 (Full Article; pdf file)
  4. Müschen M, Warskulat U, Schmidt B, Schulz WA and Häussinger D. Regulation of CD95 (Apo-1/ Fas) ligand and receptor expression in human embryonal carcinoma cells by Interferon g and all-trans Retinoic acid. Biol Chem 1998; 379: 1083-1091
  5. Josien R, Müschen M, Gilbert E, Douillard P, Heslan JM, Soulillou JP and Cuturi MC. Fas ligand, TNFa expression and apoptosis during acute allograft rejection and tolerance. Transplantation 1998; 66: 887-893n
  6. Moers C, Warskulat U, Müschen M, Even J, Niederacher D, Josien R, Koldovsky U, Beckmann MW and Häussinger D. Regulation of CD95 (Apo-1/ Fas) Ligand and receptor expression in squamous cell carcinoma by Cisplatin and Interferon g. Int J Cancer 1999; 80: 564-572 (Full Article; pdf file)
  7. Josien R, Douillard P, Guillot C, Müschen M, Chetritt J, Menoret S, Anegon I, Soulillou JP and Cuturi MC. A critical role for Transforming Growth Factor b (TGF-b) in donor transfusion-induced allograft tolerance. J Clin Invest 1998; 102: 1920-1926 (Full Article; pdf file)
  8. Müschen M, Warskulat U, Peters-Regehr T, Bode J, Kubitz R and Häussinger D. Involvement of CD95 (Apo-1/ Fas) ligand expressed by rat Kupffer cells in hepatic immunoregulation. Gastroenterology 1999; 116: 666-677 (Full Article; pdf file)
  9. Müschen M, Moers C, Warskulat U, Josien R, Even J, Lim A, Niederacher D, Betz B, Beckmann MW and Häussinger D. CD95 ligand expression in dedifferentiated breast cancer. J Pathol 1999; 189: 378-386 (Full Article; pdf file)
  10. Müschen M, Warskulat U, Even J, Perniok A, Moers C, Kismet B, Temizkan N, Simon D, Schneider M and Häussinger D. Involvement of soluble CD95 in Churg-Strauss syndrome. Am J Pathol 1999; 155: 915-925 (Full Article; pdf file)
  11. Müschen M, Rajewsky K, Bräuninger A, Baur AS, Oudejans JJ, Roers A, Hansmann ML and Küppers R. Rare occurrence of classical Hodgkin's disease as a T cell lymphoma. J Exp Med 2000; 191: 387-394 (Full Article; pdf file)
  12. Müschen M, Moers C, Warskulat U, Even J, Niederacher D and Beckmann MW. CD95 ligand expression as a mechanism of immune escape in breast cancer. Immunology 2000; 99: 69-77 (Full Article; pdf file)
  13. Müschen M, Niederacher D, Moers C, Warskulat U and Beckmann MW. Defining CD95 as a tumor suppressor gene. J Mol Med 2000; 78: 312-325 (Full Article; pdf file)
  14. Müschen M, Beckmann MW. CD95 ligand expression as a criterion of malignant transformation in breast cancer. J Pathol 2000; 191: 468-469 (Full Article; pdf file)>
  15. Müschen M, Re D, Bräuninger A, Wolf J, Hansmann ML, Diehl V, Küppers R, Rajewsky K. Somatic mutations of the CD95 gene in Hodgkin- and Reed-Sternberg cells. Cancer Res 2000; 60: 5460-5463 (Full Article; pdf file)
  16. Müschen M, Re D, Jungnickel B, Diehl V, Rajewsky K, Küppers R. Somatic mutations of the CD95 gene in human B cells as a side-effect of the germinal center reaction. J Exp Med 2001; 192: 1833-1839 (Full Article; pdf file)
  17. Re D, Müschen M, Ahmadi T, Wickenhauser C, Staratschek-Jox A, Diehl V, Wolf J. Oct-2 and Bob-1 deficiency in Hodgkin- and Reed-Sternberg cells. Cancer Res 2001; 61: 2080-2084 (Full Article; pdf file)
  18. Küppers R, Bräuninger A, Müschen M, Distler V, Hansmann ML, Rajewsky K. Evidence that Hodgkin- and Reed-Sternberg cells are not cell fusions. Blood 2001; 97: 818-821(Full Article; pdf file)
  19. Müschen M, Re D, Betz B, Moers C, Wolf J, Niederacher D, Diehl V, Beckmann MW. Resistance to CD95-mediated apoptosis in breast cancer is not due somatic mutations of the CD95 gene. Int J Cancer 2001, 92: 309-310 (Full Article; pdf file)
  20. Müschen M, Küppers R, Spieker T, Bräuninger A, Rajewsky K, Hansmann ML. Molecular single-cell analysis of Hodgkin- and Reed-Sternberg cells harboring unmutated immunoglobulin variable region genes. Lab Invest 2001, 81: 289-295 (Full Article; pdf file)
  21. Müschen M, Rajewsky K, Krönke M, Küppers R. The origin of CD95-gene mutations in B cell lymphoma. Trends in Immunology 2002, 23: 75-83 (Full Article; pdf file)
  22. Müschen M, Lee S, Zhou G, Feldhahn N, Chen JJ, Barath VS, Moers C, Krönke M, Rowley JD, Wang SM. Molecular portraits of B cell lineage commitment.Proc Natl Acad Sci USA 2002, 99: 10014-10019 (Full Article; pdf file)
  23. Feldhahn N, Schwering I, Lee S, Wartenberg M, Wang H, Wang SM, Rowley JD, Hescheler J, Krönke M, Rajewsky K, Küppers R, Müschen M. Silencing of B cell receptor signals in human naive B cells. J Exp Med 2002, 196: 1291-1305 (Full Article; pdf file)
  24. Wartenberg M, Ling FC, Müschen M, Klein F, Acker H, Gassmann M, Petrat K, Pütz V, Hescheler J, Sauer H. Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor-1 (HIF-1) and reactive oxygen species. FASEB J 2003, 17: 503-505 (Full Article; pdf file)
  25. Klein F, Feldhahn N, Lee S, Wang H, Ciuffi F, Toribio ML, Sauer H, Wartenberg M, Wang SM, Barath VS, Krönke M, Rowley JD, Müschen M. T Lymphoid differentiation in human bone marrow. Proc Natl Acad Sci USA 2003, 100: 6747-6752 (Full Article; pdf file)
  26. Schuster V and Müschen M. Epstein-Barr virus and the B cell: a secret romance. Trends Microbiol 2003, 11-243-245 (Full Article; pdf file)
  27. Feldhahn N. B cell receptor signaling. in: Modern Aspects of Immunology 2003; in press
  28. Klein F, Feldhahn N, Harder L, Wang L, Wartenberg M,Hofmann WK, Wernet P, Siebert R and Müschen M. The BCR-ABL1 kinase bypasses selection for the expression of a pre-B cell receptor in pre-B acute lymphoblastic leukemia cells. J Exp Med 2004, 199:673-685 (Full Article; pdf file)
  29. Klein F, Feldhahn N, Müschen M. Interference of BCR-ABL1 Kinase Activity with Antigen Receptor Signaling in B Cell Precursor Leukemia Cells. Cell Cycle 2004, 3:858-860 (Full Article; pdf file)
  30. Kogler G, Sensken S, Airey JA, Trapp T, Müschen M, Feldhahn N, Liedtke S, Sorg RV, Fischer J, Rosenbaum C, Greschat S, Knipper A, Bender J, Degistirici O, Gao J, Caplan AI, Colletti EJ, Almeida-Porada G, Muller HW, Zanjani E, Wernet P.A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential. J Exp Med 2004; 200:123-135. (Full Article; pdf file)
  31. Klein F, Feldhahn N, Mooster JL, Sprangers M, Hofmann WK, Wernet P, Wartenberg M and Müschen M. Tracing the pre-B to immature B cell transition in human leukemia cells reveals a coordinated sequence of primary and secondary IGK gene rearrangement, IGK deletion and IGL gene rearrangement. J Immunol, 174: 367-375 (2005) (Full Article; pdf file)
  32. Su YW, Herzog S, Lotz M, Feldhahn N, Muschen M, Jumaa H.The molecular requirements for LAT-mediated differentiation and the role of LAT in limiting pre-B cell expansion. Eur J Immunol, 34: 3614-3622 (2004) (Full Article; pdf file)
  33. Feldhahn N, Klein F, Mooster JL, Hadweh P, Sprangers M,Wartenberg M, Bekhite MM, Hofmann WK, Herzog S, Jumaa H, Rowley J & Müschen M. Mimicry of a constitutively active pre-B cell receptor: Aberrant splicing links Bruton`s tyrosine kinase to BCR-ABL1 in pre-B lymphoblastic leukemia. J Exp Med, 201: 1837-1852 (2005) (Full Article; pdf file)
  34. Ndikung Bejeng Soh B, Feldhahn N, Mooster JL, Klein F & Müschen M. B lymphoid or myeloid lineage identity of cell lines derived from chronic myeloid leukemia blast crisis. Cancer Genet Cytogenet, 156: in press (2005) (Full Article; pdf file)
  35. Feldhahn N, Río P, Ndikung Bejeng Soh B, Liedtke S, Sprangers M, Klein F, Hohensee M, Wernet P, Jumaa H, HofmannWK, Hanenberg H, Rowley JD & Müschen M. Deficiency of Bruton`s tyrosine kinase in pre-B acute lymphoblastic leukemia. Proc Natl Acad Sci USA, 102: in press (2005) (Full Article; pdf file)
  36. Klein F, Sprangers M, Feldhahn N, Herzog S, Mooster JL, Jumaa H & Müschen M. BCR-ABL1-kinase activity induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells. Oncogene, 24: in press (2005) (Full Article; pdf file)
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